Molecular analysis of antimalarial therapies : from drug development to mode of action

由 Dziekan, Jerzy Michal
出版 2019

Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848

由 Chung, Zara, Lin, Jianqing, Wirjanata, Grennady, Dziekan, Jerzy Michal, El Sahili, Abbas, Preiser, Peter Rainer, Bozdech, Zbynek, Lescar, Julien
出版 2024

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay

由 Dziekan, Jerzy Michal, Yu, Han, Chen, Dan, Dai, Lingyun, Wirjanata, Grennady, Larsson, Andreas, Prabhu, Nayana, Sobota, Radoslaw Mikolaj, Bozdech, Zbynek, Nordlund, Pär
出版 2021

Plasmodium falciparum eukaryotic translation initiation factor 3 is stabilized by quinazoline-quinoline bisubstrate inhibitors

由 Dobrescu, Irina, Hammam, Elie, Dziekan, Jerzy Michal, Claës, Aurélie, Halby, Ludovic, Preiser, Peter, Bozdech, Zbynek, Arimondo, Paola B., Scherf, Artur, Nardella, Flore
出版 2024

Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmo...

由 Kucharski, Michal, Wirjanata, Grennady, Nayak, Sourav, Boentoro, Josephine, Dziekan, Jerzy Michal, Assisi, Christina, van der Pluijm, Rob W., Miotto, Olivo, Mok, Sachel, Dondorp, Arjen M., Bozdech, Zbynek
出版 2023

Genetic validation of PfFKBP35 as an antimalarial drug target

由 Thommen, Basil T., Dziekan, Jerzy Michal, Achcar, Fiona, Tjia, Seth, Passecker, Armin, Buczak, Katarzyna, Gumpp, Christin, Schmidt, Alexander, Rottmann, Matthias, Grüring, Christof, Marti, Matthias, Bozdech, Zbynek, Brancucci, Nicolas MB
出版 2024

Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome

由 Dziekan, Jerzy Michal, Wirjanata, Grennady, Dai, Lingyun, Go, Ka Diam, Yu, Han, Lim, Yan Ting, Chen, Liyan, Wang, Loo Chien, Puspita, Brenda, Prabhu, Nayana, Sobota, Radoslaw M., Nordlund, Pär, Bozdech, Zbynek
出版 2022

Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target

由 Wagner, Matthias Paulus, Formaglio, Pauline, Gorgette, Olivier, Dziekan, Jerzy Michal, Huon, Christèle, Berneburg, Isabell, Rahlfs, Stefan, Barale, Jean-Christophe, Feinstein, Sheldon I., Fisher, Aron B., Ménard, Didier, Bozdech, Zbynek, Amino, Rogerio, Touqui, Lhousseine, Chitnis, Chetan E.
出版 2023

Genomic, transcriptomic, and metabolomic analysis of Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti-cancer metabolites

由 Julca, Irene, Mutwil-Anderwald, Daniela, Manoj, Vaishnervi, Khan, Zahra, Lai, Soak Kuan, Yang, Lay K., Beh, Ing Tsyr, Dziekan, Jerzy, Lim, Yoon P., Lim, Shen Kiat, Low, Yee W., Lam, Yuen In, Tjia, Seth, Mu, Yuguang, Tan, Qiao Wen, Nuc, Przemyslaw, Choo, Le M., Khew, Gillian, Shining, Loo, Kam, Antony, Tam, James P., Bozdech, Zbynek, Schmidt, Maximilian, Usadel, Bjoern, Kanagasundaram, Yoganathan, Alseekh, Saleh, Fernie, Alisdair, Li, Hoi Y., Mutwil, Marek
出版 2023