Elucidating antibiotic permeation through the Escherichia coli outer membrane: insights from molecular dynamics

بواسطة Deylami, Javad, Chng, Shu Sin, Yong, Ee Hou
منشور في 2025

Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry

بواسطة Thong, Shuhua, Ercan, Bilge, Torte, Federico, Fong, Zhen Yang, Wong, Hui Yi Alvina, Wenk, Markus R, Chng, Shu-Sin
منشور في 2020

Novel acetamide indirectly targets mycobacterial transporter MmpL3 by proton motive force disruption

بواسطة Shetty, Annanya, Xu, Zhujun, Lakshmanan, Umayal, Hill, Jeffrey, Choong, Meng Ling, Chng, Shu-Sin, Yamada, Yoshiyuki, Poulsen, Anders, Dick, Thomas, Gengenbacher, Martin
منشور في 2019

Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition.

بواسطة Li, Ming, Phua, Zheng Yen, Xi, Yu, Xu, Zhujun, Nyantakyi, Samuel Agyei, Li, Wei, Jackson, Mary C, Wong, Ming Wah, Lam, Yulin, Chng, Shu-Sin, Go, Mei-Lin, Dick, Thomas
منشور في 2020

Depleting cationic lipids involved in antimicrobial resistance drives adaptive lipid remodeling in Enterococcus faecalis

بواسطة Rashid, Rafi, Nair, Zeus J., Chia, Dominic Ming Hao, Chong, Kelvin Kian Long, Cazenave Gassiot, Amaury, Morley, Stewart A., Allen, Doug K., Chen, Swaine L., Chng, Shu-Sin, Wenk, Markus R., Kline, Kimberly A.
منشور في 2023

Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalis

بواسطة Rashid, Rafi, Nair, Zeus Jaren, Chia, Dominic Ming Hao, Chong, Kelvin Kian Long, Gassiot, Amaury Cazenave, Morley, Stewart A, Allen, Doug K, Chen, Swaine L, Chng, Shu Sin, Wenk, Markus R, Kline, Kimberly A
منشور في 2023

Structure-function characterization of the conserved regulatory mechanism of the Escherichia coli M48 metalloprotease BepA

بواسطة Bryant, Jack A., Cadby, Ian T., Chong, Zhi-Soon, Boelter, Gabriela, Sevastsyanovich, Yanina R., Morris, Faye C., Cunningham, Adam F., Kritikos, George, Meek, Richard W., Banzhaf, Manuel, Chng, Shu-Sin, Lovering, Andrew L., Henderson, Ian R.
منشور في 2022

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

بواسطة Goodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A., Henderson, Ian R.
منشور في 2022