Mitochondrial abnormalities-A link to idiosyncratic drug hepatotoxicity?

بواسطة Boelsterli, U.A., Lim, P.L.K.
منشور في 2011

Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities

بواسطة Ong, M.M.K., Latchoumycandane, C., Boelsterli, U.A.
منشور في 2011

Bioactivation and hepatotoxicity of nitroaromatic drugs

بواسطة Boelsterli, U.A., Ho, H.K., Zhou, S., Leow, K.Y.
منشور في 2014

Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized hum...

بواسطة Lim, M.S., Lim, P.L.K., Gupta, R., Boelsterli, U.A.
منشور في 2011

Drug acyl glucuronides: Reactivity and analytical implication

بواسطة Yang, X.-X., Hu, Z.-P., Boelsterli, U.A., Zhou, S.-F.
منشور في 2014

The mitochondrial superoxide/thioredoxin-2/ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes

بواسطة Lim, P.I.K., Liu, J., Go, M.I., Boelsterli, U.A.
منشور في 2014

The SOD2 mutant mouse as a model for oxidative stress: A functional proteomics perspective

بواسطة Lee, Y.H., Chung, M.C.M., Lin, Q., Boelsterli, U.A.
منشور في 2011

Proteomics profiling of hepatic mitochondria in heterozygous Sod2+/-mice, an animal model of discreet mitochondrial oxidative stress

بواسطة Yie, H.L., Boelsterli, U.A., Lin, Q., Chung, M.C.M.
منشور في 2011

Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/- mice: Two-stage oxidative injury

بواسطة Lee, Y.H., Chung, M.C.M., Lin, Q., Boelsterli, U.A.
منشور في 2014

Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/-mice: Two-stage oxidative injury

بواسطة Lee, Y.H., Boelsterli, U.A., Chung, M.C.M., Lin, Q.
منشور في 2011

The SOD2 mutant mouse as a model for oxidative stress: A functional proteomics perspective

بواسطة Lee, Y.H., Lin, Q., Boelsterli, U.A., Chung, M.C.M.
منشور في 2014

Oxidative bioactivation and toxicity of leflunomide in immortalized human hepatocytes and kinetics of the non-enzymatic conversion to its major metabolite, A77 1726

بواسطة Seah, Q.M., New, L.-S., Chan, E.C.Y., Boelsterli, U.A.
منشور في 2014

Proteomics profiling of hepatic mitochondria in heterozygous Sod2 +/- mice, an animal model of discreet mitochondrial oxidative stress

بواسطة Yie, H.L., Boelsterli, U.A., Lin, Q., Chung, M.C.M.
منشور في 2014

Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury

بواسطة Latchoumycandane, C., Goh, C.W., Ong, M.M.K., Boelsterli, U.A.
منشور في 2011

Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometry

بواسطة New, L.-S., Saha, S., Ong, M.M.K., Boelsterli, U.A., Chan, E.C.Y.
منشور في 2014

Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometry

بواسطة New, L.-S., Saha, S., Boelsterli, U.A., CHAN CHUN YONG,ERIC, Ong, M.M.K.
منشور في 2011

Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2+/-mice

بواسطة Ong, M.M.K., Wang, A.S., Leow, K.Y., Khoo, Y.M., Boelsterli, U.A.
منشور في 2011

Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes

بواسطة Latchoumycandane, C., Seah, Q.M., Tan, R.C.H., Boelsterli, U.A., Sattabongkot, J., Beerheide, W.
منشور في 2011

Mitochondrial permeability transition as a source of superoxide anion induced by the nitroaromatic drug nimesulide in vitro

بواسطة Tay, V.K.S., Wang, A.S., Leow, K.Y., Ong, M.M.K., Boelsterli, U.A., Wong, K.P.
منشور في 2011

Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids

بواسطة Bian, H.S., Ngo, S.Y.Y., Tan, W., Wong, C.H., Tan, T.M.C., Boelsterli, U.A.
منشور في 2011