Mitochondrial abnormalities-A link to idiosyncratic drug hepatotoxicity?

by Boelsterli, U.A., Lim, P.L.K.
Published 2011

Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities

by Ong, M.M.K., Latchoumycandane, C., Boelsterli, U.A.
Published 2011

Bioactivation and hepatotoxicity of nitroaromatic drugs

by Boelsterli, U.A., Ho, H.K., Zhou, S., Leow, K.Y.
Published 2014

Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized hum...

by Lim, M.S., Lim, P.L.K., Gupta, R., Boelsterli, U.A.
Published 2011

Drug acyl glucuronides: Reactivity and analytical implication

by Yang, X.-X., Hu, Z.-P., Boelsterli, U.A., Zhou, S.-F.
Published 2014

The mitochondrial superoxide/thioredoxin-2/ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes

by Lim, P.I.K., Liu, J., Go, M.I., Boelsterli, U.A.
Published 2014

The SOD2 mutant mouse as a model for oxidative stress: A functional proteomics perspective

by Lee, Y.H., Chung, M.C.M., Lin, Q., Boelsterli, U.A.
Published 2011

Proteomics profiling of hepatic mitochondria in heterozygous Sod2+/-mice, an animal model of discreet mitochondrial oxidative stress

by Yie, H.L., Boelsterli, U.A., Lin, Q., Chung, M.C.M.
Published 2011

Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/- mice: Two-stage oxidative injury

by Lee, Y.H., Chung, M.C.M., Lin, Q., Boelsterli, U.A.
Published 2014

Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/-mice: Two-stage oxidative injury

by Lee, Y.H., Boelsterli, U.A., Chung, M.C.M., Lin, Q.
Published 2011

The SOD2 mutant mouse as a model for oxidative stress: A functional proteomics perspective

by Lee, Y.H., Lin, Q., Boelsterli, U.A., Chung, M.C.M.
Published 2014

Oxidative bioactivation and toxicity of leflunomide in immortalized human hepatocytes and kinetics of the non-enzymatic conversion to its major metabolite, A77 1726

by Seah, Q.M., New, L.-S., Chan, E.C.Y., Boelsterli, U.A.
Published 2014

Proteomics profiling of hepatic mitochondria in heterozygous Sod2 +/- mice, an animal model of discreet mitochondrial oxidative stress

by Yie, H.L., Boelsterli, U.A., Lin, Q., Chung, M.C.M.
Published 2014

Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury

by Latchoumycandane, C., Goh, C.W., Ong, M.M.K., Boelsterli, U.A.
Published 2011

Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometry

by New, L.-S., Saha, S., Ong, M.M.K., Boelsterli, U.A., Chan, E.C.Y.
Published 2014

Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometry

by New, L.-S., Saha, S., Boelsterli, U.A., CHAN CHUN YONG,ERIC, Ong, M.M.K.
Published 2011

Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2+/-mice

by Ong, M.M.K., Wang, A.S., Leow, K.Y., Khoo, Y.M., Boelsterli, U.A.
Published 2011

Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes

by Latchoumycandane, C., Seah, Q.M., Tan, R.C.H., Boelsterli, U.A., Sattabongkot, J., Beerheide, W.
Published 2011

Mitochondrial permeability transition as a source of superoxide anion induced by the nitroaromatic drug nimesulide in vitro

by Tay, V.K.S., Wang, A.S., Leow, K.Y., Ong, M.M.K., Boelsterli, U.A., Wong, K.P.
Published 2011

Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids

by Bian, H.S., Ngo, S.Y.Y., Tan, W., Wong, C.H., Tan, T.M.C., Boelsterli, U.A.
Published 2011