Cost-minimization analysis of sequential genetic testing versus targeted next-generation sequencing gene panels in patients with pheochromocytoma and paraganglioma

• Main Authors: Weenita Pipitprapat, Oraluck Pattanaprateep, Nareenart Iemwimangsa, Insee Sensorn, Bhakbhoom Panthan, Poramate Jiaranai, Wasun Chantratita, Kinnaree Sorapipatcharoen, Preamrudee Poomthavorn, Pat Mahachoklertwattana, Thanyachai Sura, Atchara Tunteeratum, Kanoknan Srichan, Chutintorn Sriphrapradang
• 其他作者: Faculty of Medicine Ramathibodi Hospital, Mahidol University
• 格式: Article
• 出版: 2022
• 主題: Medicine
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/78679

Introduction: Pheochromocytomas and paragangliomas (PPGLs) are highly heritable tumours, with up to 40% of cases carrying germline variants. Current guidelines recommend genetic testing for all patients with PPGLs. Next-generation sequencing (NGS) enables accurate, fast, and inexpensive genetic test...