A comparative study of whole genome amplification and low-template DNA profiling

• Main Authors: Hong Han Lim, Korapin Srisiri, Budsaba Rerkamnuaychoke, Achirapa Bandhaya
• Other Authors: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50005

© 2019 Elsevier B.V. Generation of high-quality STR profiles from trace amounts of cells remains challenging. Although increasing the number of PCR cycles improves the sensitivity of STR analysis, stochastic effects may complicate interpretation and deem the profiles inconclusive. Whole Genome Ampli...