Solid-Phase Mediated Methodology to Incorporate Drug into Intermolecular Spaces of Cyclodextrin Columns in Polyethylene Glycol/Cyclodextrin-Polypseudorotaxanes by Cogrinding and Subsequent Heating

• Main Authors: Marina Ogawa, Kenjirou Higashi, Sachie Namiki, Nan Liu, Keisuke Ueda, Waree Limwikrant, Keiji Yamamoto, Kunikazu Moribe
• 其他作者: Chiba University
• 格式: Article
• 出版: 2018
• 主題: Chemistry
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/42233

© 2017 American Chemical Society. In this study, a new preparation method was developed to obtain drug/(polyethylene glycol/cyclodextrin-polypseudorotaxane (PEG/CD-PPRX)) complexes in which drugs were incorporated into the intermolecular spaces of CD columns in PEG/CD-PPRXs. This method was solid-ph...