The induction of cyclooxygenase-2 by 17β-estradiol in endothelial cells is mediated through protein kinase C

• Main Authors: P. Akarasereenont, K. Techatraisak, A. Thaworn, S. Chotewuttakorn
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/25851

Objective and Design: We investigated whether estrogen affected COX isoform expressed in human umbilical vein endothelial cells (HUVEC). Materials and Methods: HUVEC were grown to confluence and replaced with fresh medium containing 17β-estradiol (0.001, 0.01, 0.1 and 1 nM) or 17β-estradiol (1 nM) p...