In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos)

• Main Authors: Mayfong Mayxay, Marion Barends, Alan Brockman, Anchalee Jaidee, Shalini Nair, Dan Sudimack, Tiengkham Pongvongsa, Samlane Phompida, Rattanaxay Phetsouvanh, Tim Anderson, Nicholas J. White, Paul N. Newton
• 其他作者: Mahosot Hospital
• 格式: Article
• 出版: 2018
• 主題: Immunology and Microbiology; Medicine
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/24592

Recent drug trials in Laos have shown high levels of Plasmodium falciparum resistance to chloroquine, but there are no published data on in vitro antimalarial drug susceptibility. We used the double-site enzyme-linked pLDH immunodetection (DELI) assay to estimate the in vitro antimalarial drug susce...