A direct catalytic asymmetric Mannich-type reaction via a dinuclear zinc catalyst: Synthesis of either anti- or syn-α-hydroxy-β-amino ketones
The use of imines bearing a hydrolyzable nitrogen substituent in direct asymmetric Mannich reactions with α-hydroxyketones is developed. Previous work focused on the use of N-arylimines or nonenolizable imines, and the latter with only methoxy-substituted α-hydroxyacetophenones. Using a dinuclear ca...
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Main Authors: | Barry M. Trost, Jaray Jaratjaroonphong, Vichai Reutrakul |
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其他作者: | Stanford University |
格式: | Article |
出版: |
2018
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在線閱讀: | https://repository.li.mahidol.ac.th/handle/123456789/23177 |
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