Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos
The diagnostic utility of immunochromatographic (Leptotek) and enzyme-linked immunosorbent assay (ELISA; Panbio) tests for the detection of Leptospira immunoglobulin M antibodies was assessed in febrile adults admitted in Vientiane, Laos. Both tests demonstrated poor diagnostic accuracy using admiss...
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th-mahidol.229732018-08-20T14:11:09Z Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos Stuart D. Blacksell Lee Smythe Rattanaphone Phetsouvanh Michael Dohnt Rudy Hartskeerl Meegan Symonds Andrew Slack Manivanh Vongsouvath Viengmone Davong Olay Lattana Simmaly Phongmany Valy Keolouangkot Nicholas J. White Nicholas P.J. Day Paul N. Newton Mahosot Hospital University of Oxford Mahidol University World Health Organization, Australia Royal Tropical Institute - KIT Biochemistry, Genetics and Molecular Biology Immunology and Microbiology Medicine The diagnostic utility of immunochromatographic (Leptotek) and enzyme-linked immunosorbent assay (ELISA; Panbio) tests for the detection of Leptospira immunoglobulin M antibodies was assessed in febrile adults admitted in Vientiane, Laos. Both tests demonstrated poor diagnostic accuracy using admission serum (Leptotek sensitivity of 47.3% and specificity of 75.5%: ELISA sensitivity of 60.9% and specificity of 65.6%) compared to the Leptospira "gold standard" microscopic agglutination test. Copyright © 2006, American Society for Microbiology. All Rights Reserved. 2018-08-20T06:49:47Z 2018-08-20T06:49:47Z 2006-10-01 Article Clinical and Vaccine Immunology. Vol.13, No.10 (2006), 1166-1169 10.1128/CVI.00219-06 15566811 2-s2.0-33750334679 https://repository.li.mahidol.ac.th/handle/123456789/22973 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33750334679&origin=inward |
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Mahidol University |
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Asia |
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Thailand Thailand |
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Mahidol University Library |
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Mahidol University Institutional Repository |
| topic |
Biochemistry, Genetics and Molecular Biology Immunology and Microbiology Medicine |
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Biochemistry, Genetics and Molecular Biology Immunology and Microbiology Medicine Stuart D. Blacksell Lee Smythe Rattanaphone Phetsouvanh Michael Dohnt Rudy Hartskeerl Meegan Symonds Andrew Slack Manivanh Vongsouvath Viengmone Davong Olay Lattana Simmaly Phongmany Valy Keolouangkot Nicholas J. White Nicholas P.J. Day Paul N. Newton Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos |
| description |
The diagnostic utility of immunochromatographic (Leptotek) and enzyme-linked immunosorbent assay (ELISA; Panbio) tests for the detection of Leptospira immunoglobulin M antibodies was assessed in febrile adults admitted in Vientiane, Laos. Both tests demonstrated poor diagnostic accuracy using admission serum (Leptotek sensitivity of 47.3% and specificity of 75.5%: ELISA sensitivity of 60.9% and specificity of 65.6%) compared to the Leptospira "gold standard" microscopic agglutination test. Copyright © 2006, American Society for Microbiology. All Rights Reserved. |
| author2 |
Mahosot Hospital |
| author_facet |
Mahosot Hospital Stuart D. Blacksell Lee Smythe Rattanaphone Phetsouvanh Michael Dohnt Rudy Hartskeerl Meegan Symonds Andrew Slack Manivanh Vongsouvath Viengmone Davong Olay Lattana Simmaly Phongmany Valy Keolouangkot Nicholas J. White Nicholas P.J. Day Paul N. Newton |
| format |
Article |
| author |
Stuart D. Blacksell Lee Smythe Rattanaphone Phetsouvanh Michael Dohnt Rudy Hartskeerl Meegan Symonds Andrew Slack Manivanh Vongsouvath Viengmone Davong Olay Lattana Simmaly Phongmany Valy Keolouangkot Nicholas J. White Nicholas P.J. Day Paul N. Newton |
| author_sort |
Stuart D. Blacksell |
| title |
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos |
| title_short |
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos |
| title_full |
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos |
| title_fullStr |
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos |
| title_full_unstemmed |
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos |
| title_sort |
limited diagnostic capacities of two commercial assays for the detection of leptospira immunoglobulin m antibodies in laos |
| publishDate |
2018 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/22973 |
| _version_ |
1763494587053113344 |