Development of a whole-cell biocatalyst co-expressing P450 monooxygenase and glucose dehydrogenase for synthesis of epoxyhexane

• Main Authors: Akasit Siriphongphaew, Pimpaya Pisnupong, Jirarut Wongkongkatep, Pranee Inprakhon, Alisa S. Vangnai, Kohsuke Honda, Hisao Ohtake, Junichi Kato, Jun Ogawa, Sakayu Shimizu, Vlada B. Urlacher, Rolf D. Schmid, Thunyarat Pongtharangkul
• 其他作者: Mahidol University
• 格式: Article
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/13688

Oxygenases-based Escherichia coli whole-cell biocatalyst can be applied for catalysis of various commercially interesting reactions that are difficult to achieve with traditional chemical catalysts. However, substrates and products of interest are often toxic to E. coli, causing a disruption of cell...