Antifungal, cytotoxic activities and docking studies of 2,5-dimercapto-1,3,4-thiadiazole derivatives

• المؤلفون الرئيسيون: Weerasak Samee, Opa Vajragupta
• مؤلفون آخرون: Srinakharinwirot University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/12827
• المؤسسة: Mahidol University

A series of 2,5-dimercapto-1,3,4-thiadiazole derivatives (compounds 1 to 10) were prepared by nucleophilic substitution reaction between 2,5-dimercapto-1,3,4-thiadiazole and chloroheterocyclic compounds in methanol and in the presence of potassium carbonate (compounds 1 to 5 and 8) or metallic sodiu...