Offset C60 fullerene encapsulated inside Goldberg type i fullerenes

The use of nanotechnology in pharmaceutical is an important topic in order to transport drugs to the targeted cells. However, there are a few studies for the mechanics of encapsulated tiny drug molecules into a nano-size capsule. In this paper, we determine the encapsulation of an assumed spherical...

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Main Authors: Duangkamon Baowan, Noraphon Bunkluarb
其他作者: Mahidol University
格式: Conference or Workshop Item
出版: 2018
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在線閱讀:https://repository.li.mahidol.ac.th/handle/123456789/12126
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總結:The use of nanotechnology in pharmaceutical is an important topic in order to transport drugs to the targeted cells. However, there are a few studies for the mechanics of encapsulated tiny drug molecules into a nano-size capsule. In this paper, we determine the encapsulation of an assumed spherical drug molecule inside a spherical capsule using mathematical model, where both molecules are assumed to be carbon fullerenes with different sizes. Moreover, Lennard-Jones potential function together with the continuous approximation is employed to determine the energy of the system which gives rise to the equilibrium position of the drug molecule in the capsule. Further, an analytical solution is obtained as a function of the molecule radii. This research might be considered as a first step to investigate the encapsulation of drug molecule in a nanocapsule for the medical research.