Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses

• Main Authors: Pornapat Surasombatpattana, Rodolphe Hamel, Sirilaksana Patramool, Natthanej Luplertlop, Frédéric Thomas, Philippe Desprès, Laurence Briant, Hans Yssel, Dorothée Missé
• 其他作者: IRD Centre de Montpellier
• 格式: Article
• 出版: 2018
• 主題: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/11264

Dengue virus (DENV) infection is the most prevalent mosquito-borne viral diseases in the world. Vector-mediated transmission of DENV is initiated when a blood-feeding female Aedes mosquito injects saliva, together with the virus, into the skin of its mammalian host. Understanding the role of skin im...