Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications

• Main Authors: Ong, Wei-Yi, Go, Mei-Lin, Wang, De-Yun, Cheah, Irwin Kee-Mun, Halliwell, Barry
• Other Authors: ANATOMY
• Format: Article
• Language: English
• Published: SPRINGER 2022
• Subjects: Science & Technology; Life Sciences & Biomedicine; Neurosciences; Neurosciences & Neurology; SARS-CoV-2; COVID-19; COVID; SARS; Coronavirus; Antimalarials; Statins; Chloroquine; Hydroxychloroquine; Quinacrine; Aminoacridine; Cytosolic phospholipase A(2); cPLA(2); Secretory phospholipase A(2); sPLA(2)IID; TNF-alpha; DMT1; Iron transport; Arachidonic acid; Eicosanoids; Inflammation; Neuroinflammation; Microglia; Lysosomes; Oxidative stress; Free radical damage; Carotid body; Aortic body; Nucleus of the tractus solitarius; Glossopharyngeal nerve; Vagus nerve; Respiratory centre; Hippocampus; Stroke; Microvessels; Microcirculation; Brain endothelial cells; Vascular dementia; CYTOPLASMIC PHOSPHOLIPASE A(2); DIVALENT METAL TRANSPORTER-1; NF-KAPPA-B; RAT HIPPOCAMPUS; PLASMA 7-KETOCHOLESTEROL; ARACHIDONIC-ACID; APOLIPOPROTEIN D; NEURONAL DEATH; QUINACRINE; CORONAVIRUS
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/218884

10.1007/s12035-020-02093-z