A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects

A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects

10.1007/s40268-016-0143-y

Saved in:

書目詳細資料
Main Authors:	Lee, KO, Khoo, CM, Chowbay, B, Chan, YH, Sim, MK
其他作者:	DEAN'S OFFICE (MEDICINE)
格式:	Article
出版:	Springer Science and Business Media LLC 2021
主題:	Administration, Oral Adult Angiotensin I Dose-Response Relationship, Drug Female Humans Male Middle Aged Young Adult
在線閱讀:	https://scholarbank.nus.edu.sg/handle/10635/205890
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

相似書籍

Des-aspartate-angiotensin I and angiotensin AT1receptors in rat cardiac ventricles
由: Sim, M.-K., et al.
出版: (2011)

Effects of des-aspartate-angiotensin I on the expression of angiotensin AT1and AT2receptors in ventricles of hypertrophic rat hearts
由: Chen, W.S., et al.
出版: (2012)

Reduction of infarct size by orally administered des-aspartate-angiotensin I in the ischemic reperfused rat heart
由: Wen, Q., et al.
出版: (2012)

Effects of des-aspartate-angiotensin I on the actions of angiotensin III in the renal and mesenteric vasculature of normo- and hypertensive rats
由: Mustafa, M.R., et al.
出版: (2012)

Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ-induced diabetic rats
由: Dharmani, M., et al.
出版: (2011)

Involvement of AT1 angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature
由: Dharmani, M., et al.
出版: (2011)

Effects of des-aspartate-angiotensin I on neointima growth and cardiovascular hypertrophy
由: Kwoon, S.M., et al.
出版: (2012)

Novel central action of des-Asp-angiotensin I
由: Sim, M.K., et al.
出版: (2012)

Formation of des-Asp-angiotensin I in the hypothalamic extract of normo- and hypertensive rats
由: Sim, M.K., et al.
出版: (2012)

Actions of D-amino acid-substituted analogues of des-Asp-angiotensin I on the central pressor action of angiotensin III
由: Radhakrishnan, R., et al.
出版: (2012)

Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III
由: Sim, M.K., et al.
出版: (2012)

Degradation of angiotensin I to [des-Asp1]angiotensin I by a novel aminopeptidase in the rat hypothalamus
由: Sim, M.K., et al.
出版: (2012)

Bioavailability of Orally Administered Des-Aspartate-Angiotensin I in Human Subjects
由: Lee, Kok-Onn, et al.
出版: (2021)

Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice
由: Wong, Yong-Chiat, et al.
出版: (2021)

Actions of des-Asp-angiotensin I on the aortic rings of the normo- and hypertensive rats
由: Lim, B.C., et al.
出版: (2012)

Filipino emerging adults in romantic relationships: Determining relationship satisfaction through their partner's scores on the big five personality theory
由: Kwon, Soohyun, et al.
出版: (2017)

Preclinical pharmacokinetic evaluation of resveratrol trimethyl ether in sprague-dawley rats: The impacts of aqueous solubility, dose escalation, food and repeated dosing on oral bioavailability
由: Lin, H.-S., et al.
出版: (2014)

Effects of des-Asp-angiotensin I on experimentally-induced cardiac hypertrophy in rats
由: Sim, M.K., et al.
出版: (2012)

Effect of des-aspartate-angiotensin I on myocardial ischemia-reperfusion injury in rats and on release of prostanoids by human umbilical vein endothelial cells
由: WEN QIANG
出版: (2011)

Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats
由: Sim, M.K.
出版: (2012)

Angiotensins in plasma of hypertensive rats and human
由: Sim, M.K., et al.
出版: (2012)

Use of des-aspartate-angiotensin I
由: SIM, MENG KWOON
出版: (2012)

Use of des-aspartate-angiotensin I
由: SIM, MENG KWOON
出版: (2012)

The relationship between physical warmth and prosocial behaviors within a romantic relationship as moderated by adult attachment styles
由: Casugbo, Jamielle J., et al.
出版: (2017)

A Balancing Act: Negotiating Relationships in Two Contemporary Young Adult Novels from the Philippines
由: Lee, Gabriela
出版: (2014)

Endothelium-dependent response of the rabbit aorta to femtomolar concentrations of angiotensin II
由: Kuttan, S.C., et al.
出版: (2012)

Effects of des-Asp-angiotensin I on the electrically stimulated contraction of the rabbit pulmonary artery
由: Sim, M.K., et al.
出版: (2012)

Behavioral impact of national health campaigns on healthy lifestyle practices among young adults in Singapore: a cross-sectional study
由: Khow, Yong Zhi, et al.
出版: (2022)

Subtypes of losartan-sensitive angiotensin receptor in the rabbit pulmonary artery
由: Sim, M.K., et al.
出版: (2016)

Role of angiotensin II receptor antagonists in the treatment of hypertension
由: Zhu, Y.Z., et al.
出版: (2012)

Enhanced pressor response to angiotensin III in spontaneously hypertensive rats: Effects of losartan
由: Radhakrishnan, R., et al.
出版: (2012)

Pharmacokinetics of pterostilbene in Sprague-Dawley rats: The impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability
由: Yeo, S.C.M., et al.
出版: (2014)

Into the wild: A quantitative study on the conceptions of adulthood among Filipino emerging adults
由: Casidsid, Christine Deah A., et al.
出版: (2017)

Socioeconomic status and gender differences on emerging adults' view on marriage
由: Arellano, Eunice Ann A., et al.
出版: (2011)

Hookah use patterns, social influence and associated other substance use among a sample of New York City public university students
由: El Shahawy, O., et al.
出版: (2021)

Alone again, attitudes of mothers and fathers towards leaving the nest
由: Crisostomo, Kathrina, et al.
出版: (1999)

Mechanisms of Hypoglycemic action of angiotensin peptides in Diet-induced diabetic mice
由: WONG YONG CHIAT
出版: (2011)

Role of angiotensin in renal dihydrofolate reductase, GTP-cyclohydrolase 1 and nitric oxide synthase expression in renal ischemic reperfusion
由: Yuyen Seujange
出版: (2011)

Role of angiotensin in renal dihydrofolate reductase, GTP-cyclohydrolase 1 and nitric oxide synthase expression in renal ischemic reperfusion
由: Yuyen Seujange
出版: (2006)

Polymorphic inhibition of human angiotensin I-converting enzyme by enalaprilat
由: Lee, E.J.D.
出版: (2014)