C5a regulates IL-1β production and leukocyte recruitment in a murine model of monosodium urate crystal-induced peritonitis

• Main Authors: Khameneh, H.J, Ho, A.W.S, Laudisi, F, Derks, H, Kandasamy, M, Sivasankar, B, Teng, G.G, Mortellaro, A
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: complement component C3a; complement component C5a; complement component C5a receptor; cryopyrin; inflammasome; interleukin 1; interleukin 1alpha; interleukin 1beta; lipopolysaccharide; reactive oxygen metabolite; urate; animal cell; animal experiment; animal model; animal tissue; Article; cell infiltration; cell stimulation; complement activation; complement system; controlled study; cytokine production; cytokine release; disease association; gout; human; human cell; in vitro study; in vivo study; intracellular signaling; leukocyte function and characteristics; leukocyte infiltration; leukocyte recruitment; molecular dynamics; monocyte; mouse; neutrophil chemotaxis; nonhuman; peritoneum macrophage; peritonitis
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181303
• Institution: National University of Singapore

10.3389/fphar.2017.00010