Prolyl isomerase Pin1: A catalyst for oncogenesis and a potential therapeutic target in cancer

• المؤلفون الرئيسيون: Ryo, A, Liou, Y.-C, Lu, K.P, Wulf, G
• مؤلفون آخرون: BIOLOGICAL SCIENCES
• التنسيق: Review
• منشور في: 2020
• الموضوعات: antineoplastic agent; APC protein; beta catenin; cis trans isomerase; cyclin D1; DNA; juglone; phosphoprotein; proline derivative; protein p53; protein Pin 1; Ras protein; serine; threonine; transcription factor E2F; unclassified drug; Wnt protein; breast cell; carcinogenesis; cell growth; cell transformation; cis trans isomerism; conformational transition; DNA damage; drug mechanism; drug targeting; gene expression regulation; gene overexpression; human; mitogenicity; nonhuman; oncogene neu; oncogene ras; priority journal; protein function; protein motif; protein phosphorylation; protein protein interaction; protein stability; regulatory mechanism; review; signal transduction; transcription regulation; Animals; Antineoplastic Agents; beta Catenin; Catalysis; Cyclin D1; Cytoskeletal Proteins; DNA Damage; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Peptidylprolyl Isomerase; Signal Transduction; Trans-Activators; Tumor Suppressor Protein p53
• الوصول للمادة أونلاين: https://scholarbank.nus.edu.sg/handle/10635/181126

10.1242/jcs.00276