Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction

• Main Authors: Grainger, D.J, Lever, A.M.L
• Other Authors: MEDICINE
• Format: Article
• Published: BMC 2020
• Subjects: chemokine; chemokine receptor antagonist; chemokine receptor CCR5; chemokine receptor CXCR4; glycoprotein gp 120; ligand; peptide 3; unclassified drug; peptide; virus receptor; article; chemotaxis; drug mechanism; human; human cell; Human immunodeficiency virus infection; immunofluorescence; in vitro study; inhibition kinetics; leukemia cell line; protein protein interaction; receptor binding; signal transduction; cell line; drug effect; Human immunodeficiency virus 1; macrophage; metabolism; pathogenicity; synthesis; virology; Cell Line; Chemokines; Chemotaxis; HIV Envelope Protein gp120; HIV-1; Humans; Jurkat Cells; Macrophages; Peptides; Receptors, CCR5; Receptors, HIV; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178367

10.1186/1742-4690-2-23