Controlled release of dexamethasone in PCL/silk fibroin/ascorbic acid nanoparticles for the initiation of adipose derived stem cells into osteogenesis

• Main Authors: Gandhimathi, Chinnasamy, Neo, Xuan Hao Edwin, Jayaraman, Praveena, Venugopal, Jayarama Reddy, Ramakrishna, Seeram, Kumar, Srinivasan Dinesh
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2016
• 主題: Polycaprolactone; Silk fibroin; Dexamethasone release; Bone tissue engineering; Mineralization
• 在線閱讀: https://hdl.handle.net/10356/80633; http://hdl.handle.net/10220/40616

Mimicking hybrid extracellular matrix is one of the major challenges in bone tissue engineering. Biocomposite micro/nanoparticle of polycaprolactone (PCL), silk fibroin (SF), ascorbic acid (AA) and dexamethasone (DM) were fabricated by the electrospraying methods in order to generate an improved ost...