Patterning of oncogenic Ras clustering in live cells using vertically aligned nanostructure arrays

• Main Authors: Mu, Huanwen, Zeng, Yongpeng, Zhuang, Yinyin, Gao, Weibo, Zhou, Yong, Rajalingam, Krishnaraj, Zhao, Wenting
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Engineering::Chemical engineering; Nanobar; Ras Oncogene
• 在線閱讀: https://hdl.handle.net/10356/155186

As a dominant oncogenic protein, Ras is well-known to segregate into clusters on the plasma membrane for activating downstream signaling. However, current technologies for direct measurements of Ras clustering are limited to sophisticated high-resolution techniques like electron microscopy and fluor...