PERBANDINGAN MARKER INFLAMASI ANTARA SINDROMA KORONER AKUT DAN NON SINDROMA KORONER AKUT Myeloperoxidase dan High Sensitive C-Reactive Protein sebagai marker inflamasi pada dislipidemia
The number of dyslipidemia patient has rapidly increased. Dyslipidemia is a major risk factor of coronary heart disease. Chronic inflamation and endothel disfunction is factor that act in inisiation and progressiveness of coronary disease. Atherosclerosis process in coronary artery is early process...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2012
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/97469/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=53097 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | The number of dyslipidemia patient has rapidly increased. Dyslipidemia is a
major risk factor of coronary heart disease. Chronic inflamation and endothel disfunction
is factor that act in inisiation and progressiveness of coronary disease. Atherosclerosis
process in coronary artery is early process from Acute Coronary Syndrome (ACS).
Atherosclerosis is chronic inflammation disease that characteristiced with lipid infiltration
dan inflamation cell, such as macrophage derived monocyte and T limphocyte to artery
wall. Myeloperoxidase (MPO) is hemoprotein in azurophilic granule, which released to
extracelluler liquid and circulation during inflamation process.
The aims of this study is to analyze comparation between MPO
(Myeloperoxidase) and hs CRP (High Sensitive C-Reactive Protein) level as
inflammation marker of dyslipidemia non ACS and dyslipidemia ACS patients. This
study use a cross sectional design. The subject of this study is dyslipidemia non ACS
patient who came to Internal Medicine Departement and dyslipidemia ACS patient who
came to emergency care unit and analyze blood sample in Laboratory of Clinical
Pathology at dr. Moewardi Hospital Surakarta. To analyze this result we use independent
t-test/Mann withney test and Spearman/Pearson (r) correlation using computer
programme, with degree of level significancy p < 0,05, and confidence interval 95%.
Myeloperoxidase is early marker of inflamation process which happenned in
dyslipidemia non ACS and dyslipidemia ACS patients. |
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