Piperine Increases Pentagamavunon-1 Anti-cancer Activity on 4T1 Breast Cancer Through Mitotic Catastrophe Mechanism and Senescence with Sharing Targeting on Mitotic Regulatory Proteins

• Main Authors: Endah, Endah, Wulandari, Febri, Putri, Yurananda, Jenie, Riris Istighfari, Meiyanto, Edy
• 格式: Article PeerReviewed
• 語言: English
• 出版: Brieflands 2022
• 主題: Cancer Cell Biology; Cancer Diagnosis; Cancer Genetics; Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
• 在線閱讀: https://repository.ugm.ac.id/283288/1/ijpr-123820.pdf; https://repository.ugm.ac.id/283288/; https://brieflands.com/journals/iranian-journal-of-pharmaceutical-research/
• 機構: Universitas Gadjah Mada

Pentagamavunon-1 performs more potent anti-cancer effects than curcumin against various cancer cells, but it remains to be optimized. Piperine shows the activity as an enhancer of a therapeutic agent. This study expects to achieve higher effectiveness of PGV-1 on 4T1 breast cancer cells through co-t...