Kerentanan berbagai spesies nyamuk dl daerah nonendemis filariasis terhadap infeksi percobaan brugia malayi nonperiodik
ABSTRACT Filariasis in is still a public health problem with persistent transmission. Although in several areas its prevalence decreases in general transmission of filariasis persists. The transmission of filariasis is supported by the prenence of zoonotic subperiodic nocturnal and nonperiodic B. ma...
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| 格式: | Article NonPeerReviewed |
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[Yogyakarta] : Universitas Gadjah Mada
2001
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| 在線閱讀: | https://repository.ugm.ac.id/19601/ http://i-lib.ugm.ac.id/jurnal/download.php?dataId=2433 |
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| 總結: | ABSTRACT
Filariasis in is still a public health problem with persistent transmission. Although in several areas its prevalence decreases in general transmission of filariasis persists. The transmission of filariasis is supported by the prenence of zoonotic subperiodic nocturnal and nonperiodic B. malayi. The latter us a new species in Indonesia with very high endemicity in East Kalimantan. Besides its zoonotic nature, people migration makes transmission and distribution of filariasis increase. Furthermore, better transport facilities ang high mobility of people facilitate high risk of transmission if susceptible mosquitoes present in the areas. This condition makes laboratory susceptibility test of several mosquito species from nonendemic areas using experimental animal as infection source need to be done.
This series of experiment was carried out in the laboratory. M. unguiculatus is used as the infection source. It is injected subcutaneously with infective L3 of nonperiodic B. malayi. After prepatent period of 3-4 months its microfilaremi is examined before exposed to mosquitoes. The experimental subjects are several mosquito psecies from nonendemic j areas, i.e : Ae. aegypti, M. uniformis, Ar. subalbatus, Cx. quinquefasciatus, An. maculatus, An. aconitus and An. nigerrimus which all known as filarial vector in Indonesia. Ae. togoi which known as a filarial vector in the Japan and Cina as positive control. This species has been colonized in the Parasitology Laboratory of Medecine Faculty, Gadjah Mada University since 1982.
The reasults show that 5 out of 8 experimental species species {Ae. togoi, Ae. aegypti, M. uniformis, Ar. subalbatus and Cx. quinquifasciatus) are susceptible to nonperiodic B. malayi. Their susceptibility degrees are as follows : Ae. togoi (high),Ar. subalbatus (medium), M. uniformis (low), Cx. quinquefasciatus (very low), and Ae. aegi/pti (least). Anacova test gives very high sicnificancy (P=0,000) of the mosquito susceptibility degrees. Spearman's Rho test reveals that cibarial teeth have influence on susceptibility (P |
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