Analysis of acid resistance of 6,6'7-anhydroerythromycin D using FT-IRFT-IR spectrometric approach and microbial test
c16-7-Anhydroerythromycin D has been resulted from fermentation of Saccharopolyspora erythraea ATCC 11912 with additional isonicotinic hydrazide (INH) in order to produce an acidic resistant erythromycin derivative. The acid resistance analysis was carried out to the product, in series of pH, using...
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| Format: | Article NonPeerReviewed |
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[Yogyakarta] : Universitas Gadjah Mada
1999
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| Online Access: | https://repository.ugm.ac.id/17864/ http://i-lib.ugm.ac.id/jurnal/download.php?dataId=633 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | c16-7-Anhydroerythromycin D has been resulted from fermentation of Saccharopolyspora erythraea ATCC 11912 with additional isonicotinic hydrazide (INH) in order to produce an acidic resistant erythromycin derivative. The acid resistance analysis was carried out to the product, in series of pH, using FT-IR spectrometric approach and microbial test. The IR spectrogram showed the stability of the appearance of C�-carbonyl group of the product under acidic condition (pH 3-5). This results were supported by the microbial tests.
Keywords: Ab.7-Anhydroerythromycin D - FTIR-spectrophotometric analysis - Microbial test. |
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