EFEK ANTIHIPERTENSI FRAKSI TIDAK LARUT KLOROFORM EKSTRAK ETANOLIK DAUN PEGAGAN (Centella asiatica (L.) Urban) PADA TIKUS TERINDUKSI FENILEFRIN
Hypertension is a risk factor for cardiovascular diseases. In Indonesia , 22,8 % of the population suffer from hypertension. People use tradisional remedies or medicinal plants for curing hypertension, such as Centella asiatica (L) Urban). Triterpenoids and flavonoids conte...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/133748/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=74554 |
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| Summary: | Hypertension is a risk factor for cardiovascular diseases. In Indonesia , 22,8 % of
the population suffer from hypertension. People use tradisional remedies or medicinal
plants for curing hypertension, such as Centella asiatica (L) Urban). Triterpenoids and
flavonoids contents of the leaves are potensial to be developed as antihypertensive
compounds and these two chemical constituent groups have different polarities so they
can be separated by fractionation using different solvents. The triterpenoid fraction has
been reported having antihypertension effect therefore this research were emphasized on
the antihypertension effect of flavonoid fraction of leaves ethanolic extract.
The dried leaves powder was macerated with 70% ethanol and fractionated with
chloroform. Thin layer chromatogram data on silica F254 with mobile phase of
butanol |
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