GAMBARAN KEPADATAN SERABUT KOLAGEN DAN SERABUT ELASTIK PADA KULIT ANJING MUDA DAN TUA
Aging is a process of deterioration on tissue ability to maintain its normal structure and functions. Aging process will occur in all organs, and skin is no exception. Skin is the widest organ with many important functions. Aging give rise to skin wrinkles, slacken and loose of its elasticity. These...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/130173/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=70588 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | Aging is a process of deterioration on tissue ability to maintain its normal
structure and functions. Aging process will occur in all organs, and skin is no
exception. Skin is the widest organ with many important functions. Aging give
rise to skin wrinkles, slacken and loose of its elasticity. These conditions occur
due to changes in the part of the skin especially in the dermis that contains both
collagen and elastic fiber, either caused by intrinsic or extrinsic factors. Currently,
information about aging of animal skin especially dogs is only limited. This
research aims to see the visualization of collagen and elastic fiber on young and
old dogs.
There are six dogs, aged less than six months and six dogs aged more than
five years old used in this research. Biopsy is performed to take 2x2x0.5 cm3 of
the dog skin for histology sample preparation by means of Mallory stain for
collagen fiber and Verhoeff�s Elastic Fiber (Van Gieson) stain for elastic fiber.
Examination of the collagen and elastic fiber of the young and old dogs are
performed using compound light microscope. The collagen density and the
amount of elastic fiber are counted in five framings randomly selected with 400
times magnification.
Result shows there are significant differences (P<0.05) between density of
collagen fiber and elastic fiber on young and old dog skin. The result indicates
deterioration of collagen density and increasing number of elastic fiber on old
skin. Summarized to be the effect of aging process in the skin.
Key words: aging, skin, collagen fiber, elastic fiber. |
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