PERBANDINGAN ABNORMALITAS KONDUKSI SARAF PADA SUBJEK DIABETES MELITUS DENGAN ULKUS DAN TANPA ULKUS
Foot ulcer is by far the most frequently found complication of diabetes, occuring in 15% of the diabetic population, and is the most popular cause of hospital admission and lower extremity amputation of diabetic patients. The risk factors of diabetic ulcers is multifactorial, peripheral neuropathy b...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/128481/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68828 |
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| Summary: | Foot ulcer is by far the most frequently found complication of diabetes, occuring in 15%
of the diabetic population, and is the most popular cause of hospital admission and lower
extremity amputation of diabetic patients. The risk factors of diabetic ulcers is
multifactorial, peripheral neuropathy being the most dominant factor. The severity of the
neuropathy may be measured by means of electrodiagnostics. This study is aimed to
compare the electrodiagnostic abnormalities (the values of motor nerves conduction
studies [MCS] and sensory nerves conduction studies [SCS]) in diabetic subjects with and
without ulcers, and assessing the electrodiagnostic variable most associated with the
prevalence of diabetic ulcers. A cross sectional study was used on diabetic subjects that
underwent an electrodiagnostic studies. Subjects went through a MCS and SCS and were
then subjected to statistical analysed. Fifty-six subjects included in this study consisted of
23 subjects with diabetic ulcers and 33 subjects without diabetic ulcers. For MCS, there
were significantly differences in median (38,73±9,99 vs 47,15±8,77 m/s, p=0,001) and
tibial (28,76±8,48 vs 34,00±7,33 m/s, p=0,030) NCV between diabetic subjects with and
without foot ulcers. Distal latency, distal amplitude and proximal amplitude values did
not show any significant difference between the two groups. The value of NCV <80%
increases the risk of diabetic ulcers (prevalence ratio [95% CI]) 3,28 (1,08�9,99). The
study concludes, NCV slowing on diabetic subjects with ulcers is more severe than the
diabetic subjects without ulcers, and the NCV abnormality is more closely associated
with diabetic ulcers. |
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