Solvent Concentration Effect on Powder X-Ray Diffraction And Dissolution Profiles Of Acyclovir-Nicotinamide Cocrystals

• المؤلفون الرئيسيون: Dwi Setyawan, Siswandono, Agnes Nuniek Winantari, Kuni Zu’aimah
• التنسيق: مقال PeerReviewed
• اللغة: English; English
• منشور في: 2017
• الموضوعات: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; RS200-201 Pharmaceutical dosage forms
• الوصول للمادة أونلاين: http://repository.unair.ac.id/73325/1/C-4%20Artikel.pdf; http://repository.unair.ac.id/73325/2/C-4%20Validasi%20dan%20Peer%20Reviewer.pdf; http://repository.unair.ac.id/73325/

Objective : Acyclovir (ACV) is well-known antiviral agent that has absorption problem, mainly due to its poor solubility in water and oral bioavailability. To improve acyclovir physical properties, especially dissolution properties, acyclovir- nicotinamide(NCT) cocrystal was formed. Methods : ACV...