Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities

Two prenylated pterocarpans, phaseollin (1), shinpterocarpin (2) together with flavonoids, 4’-O-methyl licoflavanone (3), alpinumisoflavone (4), 8-prenyl daidzein (5), have been isolated from the stem bark of Erythrina orientalis. The structures of these compounds were determined based on UV, IR,...

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Main Authors: Tjahjandarie, Tjitjik Srie, Tanjung, Mulyadi
格式: Article PeerReviewed
語言:English
English
English
出版: Scholars Research Library 2015
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spelling id-langga.630392017-10-12T22:41:27Z http://repository.unair.ac.id/63039/ Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities Tjahjandarie, Tjitjik Srie Tanjung, Mulyadi QD Chemistry Two prenylated pterocarpans, phaseollin (1), shinpterocarpin (2) together with flavonoids, 4’-O-methyl licoflavanone (3), alpinumisoflavone (4), 8-prenyl daidzein (5), have been isolated from the stem bark of Erythrina orientalis. The structures of these compounds were determined based on UV, IR, HRESIMS, 1D and 2D NMR data. Compounds 1–5 were evaluated for their cytotoxic properties against P-388 cells, their IC values 2.55, 2.43,17.98, 4.31, and 5.82 µg/mL, respectively. Compounds 1, and 5 exhibited very high antioxidant activity against DPPH radical scavenging. Scholars Research Library 2015 Article PeerReviewed image en http://repository.unair.ac.id/63039/1/Cover.pdf text en http://repository.unair.ac.id/63039/2/Bukti%20C09.%20Phenolic%20compounds%20from%20the%20stem%20bark%20of%20Erythrina%20..........pdf text en http://repository.unair.ac.id/63039/3/Bukti%20C09%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf Tjahjandarie, Tjitjik Srie and Tanjung, Mulyadi (2015) Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities. Der Pharmacia Lettre Journal., 7 (1). pp. 206-211. ISSN 0975-413X http://www.derpharmachemica.com/
institution Universitas Airlangga
building Universitas Airlangga Library
country Indonesia
collection UNAIR Repository
language English
English
English
topic QD Chemistry
spellingShingle QD Chemistry
Tjahjandarie, Tjitjik Srie
Tanjung, Mulyadi
Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
description Two prenylated pterocarpans, phaseollin (1), shinpterocarpin (2) together with flavonoids, 4’-O-methyl licoflavanone (3), alpinumisoflavone (4), 8-prenyl daidzein (5), have been isolated from the stem bark of Erythrina orientalis. The structures of these compounds were determined based on UV, IR, HRESIMS, 1D and 2D NMR data. Compounds 1–5 were evaluated for their cytotoxic properties against P-388 cells, their IC values 2.55, 2.43,17.98, 4.31, and 5.82 µg/mL, respectively. Compounds 1, and 5 exhibited very high antioxidant activity against DPPH radical scavenging.
format Article
PeerReviewed
author Tjahjandarie, Tjitjik Srie
Tanjung, Mulyadi
author_facet Tjahjandarie, Tjitjik Srie
Tanjung, Mulyadi
author_sort Tjahjandarie, Tjitjik Srie
title Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
title_short Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
title_full Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
title_fullStr Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
title_full_unstemmed Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities
title_sort phenolic compounds from the stem bark of erythrina orientalis and their cytotoxic and antioxidant activities
publisher Scholars Research Library
publishDate 2015
url http://repository.unair.ac.id/63039/1/Cover.pdf
http://repository.unair.ac.id/63039/2/Bukti%20C09.%20Phenolic%20compounds%20from%20the%20stem%20bark%20of%20Erythrina%20..........pdf
http://repository.unair.ac.id/63039/3/Bukti%20C09%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf
http://repository.unair.ac.id/63039/
http://www.derpharmachemica.com/
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