Correlation between anti-hypertensive drugs and disease progression among moderate, severe, and critically ill COVID-19 patients in the second referral hospital in Surbaya: A retrospective cohort study

• Main Authors: Satriyo Dwi Suryantoro, -, Mochammad Thaha, -, Mutiara Rizky Hayati, -, Mochamad Yusuf Alsagaff, -, Budi Susetyo Pikir, -, Hendri Susilo, -
• Format: Article PeerReviewed
• Language: English; English; English; English
• Published: Taylor & Francis 2021
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/126090/1/12.%20Correlation%20between%20anti-hypertensive%20drugs%20and%20disease%20progression%20among%20moderate%2C%20severe%2C%20and%20critically%20ill%20COVID-19%20patients%20in%20the%20second%20referral%20hospital%20in%20Surbaya.pdf; https://repository.unair.ac.id/126090/2/12.%20Korespondensi.pdf; https://repository.unair.ac.id/126090/3/karil%2012.pdf; https://repository.unair.ac.id/126090/4/12.%20Turnitin.pdf; https://repository.unair.ac.id/126090/; https://f1000research.com/articles/10-393/v2

Background: Hypertension, as the comorbidity accompanying COVID-19, is related to angiotensin-converting enzyme 2 receptor (ACE-2R) and endothelial dysregulation which have an important role in blood pressure regulation. Other anti-hypertensive agents are believed to trigger the hyperinflammation pr...