Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer–T cell coculture models

بواسطة Mimura, Kosaku, Kua, Ley-Fang, Xiao, Jin-Fen, Asuncion, Bernadette Reyna, Nakayama, Yuko, Syn, Nicholas, Fazreen, Zul, Soong, Richie, Kono, Koji, Yong, Wei-Peng
منشور في 2022

High efficacy of BAY 1187982, an FGFR2-ADC, in overcoming drug resistance in a diffuse type gastric cancer patient-derived xenograft model with acquired resistance to pan-FGFR inhi...

بواسطة Lau, Wen Min, Teng, Eileen, Huang, Kie Kyon, Tan, Jin Wei, Teh, Ming, Yong, Wei Peng, Sommer, Anette, Schatz, Christoph A, Tan, Patrick, Chan, Shing Leng, So, Jimmy
منشور في 2019

FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway

بواسطة Yeo, Subhash, KAZUTO SUDA, HAYRI EMRAH BALCIOGLU, ZHOU SIQIN, THUYA WIN LWIN, LOH XIN YI, Jammula, PRAVEEN CHAKRAVARTHY PEETHALA, Tan, Xie, Wong, Ladoux,Benoit, Ito, YANG HE, Goh, Wang, YONG WEI PENG
منشور في 2019

Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy

بواسطة Limviphuvadh, Vachiranee, Tan, Chee Seng, Konishi, Fumikazu, Jenjaroenpun, Piroon, Xiang, Joy Shengnan, Kremenska, Yuliya, Mu, Yar Soe, Soo, Ross A., Eisenhaber, Frank, Maurer-Stroh, Sebastian, Yong, Wei Peng, Nicholas, Syn, Chin, Lee Soo
منشور في 2018

Clinical outcome and prognostic factors for Asian patients in Phase I clinical trials

بواسطة Loh, Jerold, Wu, Jiaxuan, Chieng, Jenny, Chan, Aurora, Yong, Wei-Peng, Sundar, Raghav, Lee, Soo-Chin, Wong, Andrea, Lim, Joline SJ, Tan, David SP, Soo, Ross, Goh, Boon-Cher, Tai, Bee-Choo, Chee, Cheng E
منشور في 2023

Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin +/- Trastuzumab in Advanced Solid Tumors

بواسطة Lee, Matilda Xinwei, Wong, Andrea LA, Ow, Samuel, Sundar, Raghav, Tan, David SP, Soo, Ross A, Chee, Cheng Ean, Lim, Joline SJ, Yong, Wei Peng, Lim, Siew Eng, Goh, Boon Cher, Wang, Lingzhi, Lee, Soo Chin
منشور في 2022

Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3 beta

بواسطة Lau, Wen Min, Teng, Eileen, Huang, Kie Kyon, Tan, Jin Wei, Das, Kakoli, Zang, Zhijiang, Chia, Tania, Teh, Ming, Kono, Koji, Yong, Wei Peng, Shabbir, Asim, Tay, Amy, Phua, Niam Sin, Tan, Patrick, Chan, Shing Leng, So, Jimmy Bok Yan
منشور في 2021

"3G" Trial: An RNA Editing Signature to Guide Gastric Cancer Chemotherapy

بواسطة An, Omer, Song, Yangyang, Ke, Xinyu, So, Jimmy Bok-Yan, Sundar, Raghav, Yang, Henry, Rha, Sun Young, Lee, Ming Hui, Tay, Su Ting, Ong, Xuewen, Tan, Angie Lay Keng, Ng, Matthew Chau Hsien, Tantoso, Erwin, Chen, Leilei, Tan, Patrick, Yong, Wei Peng
منشور في 2021

A novel combinatorial strategy using Seliciclib (R) and Belinostat (R) for eradication of non-small cell lung cancer via apoptosis induction and BID activation

بواسطة Ong, Pei-Shi, Wang, Lingzhi, Chia, Deborah Miao-Hui, Seah, Jolyn Yu-Xin, Kong, Li-Ren, Thuya, Win-Lwin, Chinnathambi, Arunachalam, Lau, Jie-Ying Amelia, Wong, Andrea Li-Ann, Yong, Wei-Peng, Yang, Daiwen, Ho, Paul Chi-Lui, Sethi, Gautam, Goh, Boon-Cher
منشور في 2020

Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer

بواسطة Myint, Khine, Chuang, Linda Shyue Huey, Teh, Yu Xuan, Mawan, Nur Astiana, Shi, Edward Jizhong, Mok, Michelle Meng Huang, Nuttonmanit, Napat, Matsuo, Junichi, Li, Ying, Yang, Henry, Okabe, Atsushi, Kaneda, Atsushi, Osato, Motomi, So, Jimmy Bok-Yan, Yong, Wei Peng, Tan, Patrick, Yeoh, Khay Guan, Ito, Yoshiaki
منشور في 2023

A Phase I, First-in-Human Study of PRL3-zumab in Advanced, Refractory Solid Tumors and Hematological Malignancies

بواسطة Chee, Cheng E, Ooi, Melissa, Lee, Soo-Chin, Sundar, Raghav, Heong, Valerie, Yong, Wei-Peng, Ng, Chin Hin, Wong, Andrea, Lim, Joline SJ, Tan, David SP, Soo, Ross, Tan, Joshua TC, Yang, Song, Thura, Min, Al-Aidaroos, Abdul Qader, Chng, Wee Joo, Zeng, Qi, Goh, Boon-Cher
منشور في 2023

Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling

بواسطة Wang, Lingzhi, Syn, Nicholas Li-Xun, Subhash, Vinod Vijay, Any, Yijia, Thuya, Win Lwin, Cheow, Esther Sok Hwee, Kong, Li Ren, Yu, Fenggang, Peethala, Praveen C., Wong, Andrea Li-Ann, Laljibhai, Hirpara J., Chinnathambi, Arunachalam, Ong, Pei Shi, Ho, Paul Chi-Lui, Sethi, Gautam, Yong, Wei Peng, Goh, Boon Cher
منشور في 2020

Development and validation of a serum microRNA biomarker panel for detecting gastric cancer in a high-risk population

بواسطة So, Jimmy Bok Yan, Kapoor, Ritika, Zhu, Feng, Koh, Calvin, Zhou, Lihan, Zou, Ruiyang, Tang, Yew Chung, Goo, Patrick CK, Rha, Sun Young, Chung, Hyun Cheol, Yoong, Joanne, Yap, Celestial T, Rao, Jaideepraj, Chia, Chung-King, Tsao, Stephen, Shabbir, Asim, Lee, Jonathan, Lam, Kong-Peng, Hartman, Mikael, Yong, Wei Peng, Too, Heng-Phon, Yeoh, Khay-Guan
منشور في 2021

Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair

بواسطة Matsuo, Junichi, Douchi, Daisuke, Myint, Khine, Mon, Naing Naing, Yamamura, Akihiro, Kohu, Kazuyoshi, Heng, Dede Liana, Chen, Sabirah, Mawan, Nur Astiana, Nuttonmanit, Napat, Li, Ying, Srivastava, Supriya, Ho, Shamaine Wei Ting, Lee, Nicole Yee Shin, Lee, Hong Kai, Adachi, Makoto, Tamura, Atsushi, Chen, Jinmiao, Yang, Henry, Ming Teh, So, Jimmy Bok-Yan, Yong, Wei Peng, Tan, Patrick, Yeoh, Khay Guan, Chuang, Linda Shyue Huey, Tsukita, Sachiko, Ito, Yoshiaki
منشور في 2021

A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in...

بواسطة Ho, Jingshan, Heong, Valerie, Yong, Wei Peng, Soo, Ross, Chee, Cheng Ean, Wong, Andrea, Sundar, Raghav, Thian, Yee Liang, Gopinathan, Anil, Pang, Mei Yan, Koe, Priscillia, Jeraj, Santhiay Nathan, Soe, Phyu Pyar, Soe, Mu Yar, Tang, Tiffany, Ng, Matthew CH, Tai, David WM, Tan, Tira JY, Xu, Hongmei, Chang, Hua, Landesman, Yosef, Shah, Jatin, Shacham, Sharon, Lee, Soo Chin, Tan, Daniel SW, Goh, Boon Cher, Tan, David SP
منشور في 2022

Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma

بواسطة Huang, Baohua, DENG SHUO, LOO SER YUE, ARPITA DATTA, YAP YAN LIN, Yan, Benedict, OOI CHIA HUEY, DINH THUY DUONG, ZHUO JINGLI, LALCHHANDAMI TOCHHAWNG, SUMA GOPINADHAN, Jegadeesan, Tamilarasi, TAN BOON OOI,PATRICK, SALTO-TELLEZ,MANUEL, YONG WEI PENG, SOONG CHUAN TECK,RICHIE, YEOH KHAY GUAN, GOH YAW CHONG, PETER EDWARD LOBIE, YANG HE, ALAN PREM KUMAR, Maciver, Sutherland K, SO BOK YAN,JIMMY, Yap Suen Mei,Celestial Therese
منشور في 2020

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets

بواسطة Tao, Jiong, Tan, Iain Beehuat, Deng, Niantao, Goh, Liang-Kee, Wang, Hannah, Das, Kakoli, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Lim, Kiat Hon, Lei, Zhengdeng, Goh, Glenn, Lim, Qing-Yan, Tan, Angie Lay-Keng, Poh, Dianne Yu Sin, Riahi, Sudep, Bell, Sandra, Linnartz, Ronald, Zhu, Feng, Yeoh, Khay Guan, Toh, Han Chong, Yong, Wei Peng, Cheong, Hyun Cheol, Rha, Sun Young, Boussioutas, Alex, Grabsch, Heike, Tan, Patrick, Shi, Michael M., Rozen, Steve G.
منشور في 2013

FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites

بواسطة Thuya, Win Lwin, Kong, Li Ren, Syn, Nicholas L., Ding, Ling-Wen, Cheow, Esther Sok Hwee, Wong, Regina Tong Xin, Wang, Tingting, Goh, Robby Miguel Wen-Jing, Song, Hongyan, Jayasinghe, Migara K., Le, Minh Tn, Hu, Jian Cheng, Yong, Wei-Peng, Lee, Soo-Chin, Wong, Andrea Li-Ann, Sethi, Gautam, Hung, Huynh The, Ho, Paul Chi-Lui, Thiery, Jean-Paul, Sze, Siu Kwan, Guo, Tiannan, Soo, Ross A., Yang, Henry, Lim, Yaw Chyn, Wang, Lingzhi, Goh, Boon-Cher
منشور في 2023

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

بواسطة Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
منشور في 2019

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein (vol 10, 2484, 2019)

بواسطة Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
منشور في 2021