Metabolic energy sensors as targets for designing host-directed therapies for tuberculosis

by Cheng, Catherine Y., Böhme, Julia, Singhal, Amit
Published 2019

Does oxidative stress contribute to adverse outcomes in HIV-associated TB?

by Yew, Wing-Wai, Chan, Denise Puichung, Singhal, Amit, Zhang, Ying, Lee, Shui-Shan
Published 2020

mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis

by Martinez, Nuria, Cheng, Catherine Y., Ketheesan, Natkunam, Cullen, Aidan, Tang, Yuefeng, Lum, Josephine, West, Kim, Poidinger, Michael, Guertin, David A., Singhal, Amit, Kornfeld, Hardy
Published 2019

Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes

by Martinez, Nuria, Smulan, Lorissa J., Jameson, Michael L., Smith, Clare M., Cavallo, Kelly, Bellerose, Michelle, Williams, John, West, Kim, Sassetti, Christopher M., Singhal, Amit, Kornfeld, Hardy
Published 2023

Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

by Chaudhary, Deepika, Singh, Avantika, Marzuki, Mardiana, Ghosh, Abhirupa, Kidwai, Saqib, Gosain, Tannu Priya, Chawla, Kiran, Gupta, Sonu Kumar, Agarwal, Nisheeth, Saha, Sudipto, Kumar, Yashwant, Thakur, Krishan Gopal, Singhal, Amit, Singh, Ramandeep
Published 2023

Diagnosis and biomarkers for ocular tuberculosis: from the present into the future

by Ludi, Zhang, Sule, Ashita Ashish, Samy, Ramar Perumal, Putera, Ikhwanuliman, Schrijver, Benjamin, Hutchinson, Paul Edward, Gunaratne, Jayantha, Verma, Indu, Singhal, Amit, Nora, Rina La Distia, van Hagen, P. Martin, Dik, Willem A., Gupta, Vishali, Agrawal, Rupesh
Published 2023

CD27hiCD38hi plasmablasts are activated B cells of mixed origin with distinct function

by Rouers, Angeline, Appanna, Ramapraba, Chevrier, Marion, Lum, Josephine, Lau, Mai Chan, Tan, Lingqiao, Loy, Thomas, Tay, Alicia, Sethi, Raman, Sathiakumar, Durgalakshmi, Kaur, Kaval, Böhme, Julia, Leo, Yee-Sin, Renia, Laurent, Howland, Shanshan W, Singhal, Amit, Chen, Jinmiao, Fink, Katja
Published 2022

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

by Vacca, Maurizio, Böhme, Julia, Zambetti, Lia Paola, Khameneh, Hanif Javanmard, Paleja, Bhairav S., Laudisi, Federica, Ho, Adrian W. S., Neo, Kurt, Leong, Keith Weng Kit, Marzuki, Mardiana, Lee, Bernett, Poidinger, Michael, Santambrogio, Laura, Tsenova, Liana, Zolezzi, Francesca, De Libero, Gennaro, Singhal, Amit, Mortellaro, Alessandra
Published 2018

Metformin alters human host responses to Mycobacterium tuberculosis in healthy subjects

by Lachmandas, Ekta, Eckold, Clare, Böhme, Julia, Koeken, Valerie A. C. M., Mardiana Marzuki, Blok, Bastiaan, Arts, Rob J. W., Chen, Jinmiao, Teng, Karen W. W., Ratter, Jacqueline, Smolders, Elise J., Van den Heuvel, Corina, Stienstra, Rinke, Dockrell, Hazel M., Newell, Evan, Netea, Mihai G., Singhal, Amit, Cliff, Jacqueline M., Van Crevel, Reinout
Published 2021

Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity

by Lin, Quy Xiao Xuan, Rajagopalan, Deepa, Gamage, Akshamal M., Tan, Le Min, Venkatesh, Prasanna Nori, Chan, Wharton O. Y., Kumar, Dilip, Agrawal, Ragini, Chen, Yao, Fong, Siew-Wai, Singh, Amit, Sun, Louisa J., Tan, Seow-Yen, Chai, Louis Yi Ann, Somani, Jyoti, Lee, Bernett, Renia, Laurent, Ng, Lisa F. P., Ramanathan, Kollengode, Wang, Lin-Fa, Young, Barnaby, Lye, David, Singhal, Amit, Prabhakar, Shyam
Published 2024

Doxycycline host-directed therapy in human pulmonary tuberculosis.

by MIOW QING HAO, Vallejo, Andres F, Wang, Yu, HONG JIA MEI, BAI CHEN, Teo, Felicia Sw, Wang, Alvin Dingyuan, Loh, Hong Rong, Tan Tuan Zea, Ding, Ying, She, Hoi Wah, Gan, Suay Hong, Paton, Nicholas I, Lum, Josephine, Tay, Alicia, Chee, Cynthia Be, PAUL ANANTHARAJAH TAMBYAH, Polak, Marta E, Wang, Yee Tang, Singhal, Amit, Elkington, Paul, Friedland, Jon S, CATHERINE ONG WEI MIN
Published 2021