Introduction : novel insights into TB research and drug discovery

بواسطة Grüber, Gerhard
منشور في 2020

Crystallographic and enzymatic insights into the mechanisms of Mg-ADP inhibition in the A1 complex of the A1AO ATP synthase

بواسطة Singh, Dhirendra, Grüber, Gerhard
منشور في 2018

The unique C-terminal extension of mycobacterial F-ATP synthase subunit α is the major contributor to its latent ATP hydrolysis activity

بواسطة Wong, Chui-Fann, Grüber, Gerhard
منشور في 2021

Anti-Mycobacterium abscessus activity of tuberculosis F-ATP synthase inhibitor GaMF1

بواسطة Ragunathan, Priya, Dick, Thomas, Grüber, Gerhard
منشور في 2022

The structure of subunit E of the pyrococcus horikoshii OT3 A-ATP synthase gives insight into the elasticity of the peripheral stalk

بواسطة Balakrishna, Asha Manikkoth, Hunke, Cornelia, Grüber, Gerhard
منشور في 2013

Binding properties of the anti-TB drugs bedaquiline and TBAJ-876 to a mycobacterial F-ATP synthase

بواسطة Krah, Alexander, Grüber, Gerhard, Bond, Peter. J.
منشور في 2022

Re-understanding the mechanisms of action of the anti-mycobacterial drug bedaquiline

بواسطة Sarathy, Jickky Palmae, Gruber, Gerhard, Dick, Thomas
منشور في 2020

Active site CP-loop dynamics modulate substrate binding, catalysis, oligomerization, stability, over-oxidation and recycling of 2-Cys Peroxiredoxins

بواسطة Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
منشور في 2020

Substrate-induced structural alterations of Mycobacterial mycothione reductase and critical residues involved

بواسطة Kumar, Arvind, Subramanian Manimekalai, Malathy Sony, Grüber, Gerhard
منشور في 2020

Conformational states of Zika virus non-structural protein 3 determined by molecular dynamics simulations with small-angle X-Ray scattering data

بواسطة Zhu, Guanhua, Pan, Ankita, Grüber, Gerhard, Lu, Lanyuan
منشور في 2021

Residues of helix ɑ2 are critical for catalytic efficiency of mycobacterial alkylhydroperoxide reductase subunit C

بواسطة Chong, Shi Min Sherilyn, Kamariah, Neelagandan, Grüber, Gerhard
منشور في 2021

Bedaquiline Targets the ε Subunit of Mycobacterial F-ATP Synthase

بواسطة Kundu, Subhashri, Biukovic, Goran, Grüber, Gerhard, Dick, Thomas
منشور في 2017

Molecular mechanism of the Escherichia coli AhpC in the function of a chaperone under heat-shock conditions

بواسطة Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
منشور في 2018

Essential role of the flexible linker on the conformational equilibrium of bacterial peroxiredoxin reductase for effective regeneration of peroxiredoxin

بواسطة Grüber, Gerhard, Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank
منشور في 2018

Analyzing conformational changes in single FRET-labeled A1 parts of archaeal A1AO-ATP synthase

بواسطة Sielaff, Hendrik, Singh, Dhirendra, Grüber, Gerhard, Börsch, Michael
منشور في 2018

Conformational dynamics of the rotary subunit F in the A3B3DF complex of Methanosarcina mazei Gö1 A-ATP synthase monitored by single-molecule FRET

بواسطة Singh, Dhirendra, Sielaff, Hendrik, Börsch, Michael, Grüber, Gerhard
منشور في 2017

Cryo-EM structure of the Mycobacterium abscessus F1-ATPase

بواسطة Wong, Chui Fann, Leow, Chen Yen, Grüber, Gerhard
منشور في 2023

Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery

بواسطة Harikishore, Amaravadhi, Mathiyazakan, Vikneswaran, Pethe, Kevin, Grüber, Gerhard
منشور في 2023

Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study

بواسطة Srinivasaraghavan, Kannan, Nacro, Kassoum, Grüber, Gerhard, Verma, Chandra Shekhar
منشور في 2016

Variations of the Mycobacterium abscessus F-ATP synthase subunit a-c interface alter binding and potency of the anti-TB drug bedaquiline

بواسطة Krah, Alexander, Ragunathan, Priya, Bond, Peter J., Grüber, Gerhard
منشور في 2023