The genetics of Parkinson's disease.

由 Lim K.L., Dawson V.L., Dawson T.M.
出版 2018

Parkin-mediated lysine 63-linked polyubiquitination: A link to protein inclusions formation in Parkinson's and other conformational diseases?

由 Lim, K.-L., Dawson, V.L., Dawson, T.M.
出版 2014

The cast of molecular characters in Parkinson's disease: Felons, conspirators, and suspects

由 Lim K.L., Dawson V.L., Dawson T.M.
出版 2018

Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy

由 Tan, J.M.M., Wong, E.S.P., Dawson, V.L., Dawson, T.M., Lim, K.-L.
出版 2014

The 350-fold compacted Fugu parkin gene is structurally and functionally similar to human Parkin

由 Yu, W.-P., Tan, J.M.M., Chew, K.C.M., Oh, T., Kolatkar, P., Venkatesh, B., Dawson, T.M., Lim, K.L.
出版 2014

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin

由 Sriram S.R., Li X., Ko H.S., Chung K.K.K., Wong E., Lim K.L., Dawson V.L., Dawson T.M.
出版 2018

Loss of locus coeruleus neurons and reduced startle in parkin null mice

由 Von Coelln R., Thomas B., Savitt J.M., Lim K.L., Sasaki M., Hess E.J., Dawson V.L., Dawson T.M.
出版 2018

Parkin ubiquitinates the ?-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease

由 Chung K.K.K., Zhang Y., Lim K.L., Tanaka Y., Huang H., Gao J., Ross C.A., Dawson V.L., Dawson T.M.
出版 2018

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

由 Wong, E.S.P., Tan, J.M.M., Soong, W.-E., Hussein, K., Nukina, N., Dawson, V.I., Dawson, T.M., Cuervo, A.M., Lim, K.-L.
出版 2014

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

由 West A.B., Moore D.J., Choi C., Andrabi S.A., Li X., Dikeman D., Biskup S., Zhang Z., Lim K.-L., Dawson V.L., Dawson T.M.
出版 2018

Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations

由 Wong, E.S.P., Tan, J.M.M., Wang, C., Zhang, Z., Tay, S.-P., Zaiden, N., Han, S.K., Dawson, V.L., Dawson, T.M., Lim, K.-L.
出版 2014

Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila

由 Ng, C.-H., Mok, S.Z.S., Koh, C., Ouyang, X., Fivaz, M.L., Tan, E.-K., Dawson, V.L., Dawson, T.M., Yu, F., Lim, K.-L.
出版 2014

Novel Monoclonal Antibodies Demonstrate Biochemical Variation of Brain Parkin with Age

由 Pawlyk A.C., Giasson B.I., Sampathu D.M., Perez F.A., Lim K.L., Dawson V.L., Dawson T.M., Palmiter R.D., Trojanowski J.Q., Lee V.M.-Y.
出版 2018

Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations

由 Wang, C., Tan, J.M.M., Ho, M.W.L., Zaiden, N., Siew, H.W., Chew, C.L.C., Pei, W.E., Tit, M.L., Dawson, T.M., Kah, L.L.
出版 2014

Inclusion body formation and neurodegeneration are parkin independent in a mouse model of ?-synucleinopathy

由 Von Coelln R., Thomas B., Andrabi S.A., Kah L.L., Savitt J.M., Saffary R., Stirling W., Bruno K., Hess E.J., Lee M.K., Dawson V.L., Dawson T.M.
出版 2018

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: Implications for lewy body formation

由 Kah, L.L., Chew, K.C.M., Tan, J.M.M., Wang, C., Chung, K.K.K., Zhang, Y., Tanaka, Y., Smith, W., Engelender, S., Ross, C.A., Dawson, V.L., Dawson, T.M.
出版 2014

Enhanced autophagy from chronic toxicity of iron and mutant A53T α-synuclein: Implications for neuronal cell death in parkinson disease

由 Chew, K.C.M., Ang, E.-T., Tai, Y.K., Tsang, F., Lo, S.Q., Ong, E., Ong, W.-Y., Shen, H.-M., Lim, K.-L., Dawson, V.L., Dawson, T.M., Soong, T.W.
出版 2014

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

由 Wang, C., Chew, K.C.M., Tay, S.-P., Ho, M.W.L., Lim, K.-L., Lim, T.-M., Tsang, F., Soong, T.-W., Ko, H.S., Thomas, B., Dawson, V.L., Dawson, T.M., Troncoso, J., Pletnikova, O.
出版 2011

SEPT5_v2 is a parkin-binding protein

由 Choi P., Snyder H., Petrucelli L., Theisler C., Chong M., Zhang Y., Lim K., Chung K.K.K., Kehoe K., D'Adamio L., Lee J.M., Cochran E., Bowser R., Dawson T.M., Wolozin B.
出版 2018

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

由 Tan, J.M.M., Wong, E.S.P., Kirkpatrick, D.S., Pletnikova, O., Ko, H.S., Tay, S.-P., Ho, M.W.L., Troncoso, J., Gygi, S.P., Lee, M.K., Dawson, V.L., Dawson, T.M., Lim, K.-L.
出版 2014