Targeting epigenetics using synthetic lethality in precision medicine

by Chen, ES
Published 2023

Regulation of centromeric heterochromatin in the cell cycle by phosphorylation of histone H3 tyrosine 41

by Ren, B, Chen, ES
Published 2023

GRANT Motif Regulates CENP-A Incorporation and Restricts RNA Polymerase II Accessibility at Centromere

by Tan, HL, Chen, ES
Published 2023

Molecular mechanisms in governing genomic stability and tumor suppression by the SETD2 H3K36 methyltransferase

by Lam, UTF, Chen, ES
Published 2023

Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs

by Jackson, RA, Chen, ES
Published 2023

C1D family proteins in coordinating RNA processing, chromosome condensation and DNA damage response

by Jackson, R.A, Wu, J.S, Chen, E.S
Published 2020

cGAS-STING pathway in oncogenesis and cancer therapeutics

by Hoong, BYD, Gan, YH, Liu, H, Chen, ES
Published 2021

N-terminus does not govern protein turnover of schizosaccharomyces pombe cenp-a

by Tan, H.L., Zeng, Y.B., Chen, E.S.
Published 2021

Stage-specific protein-domain mutational profile of invasive ductal breast cancer

by Yu, T., Choi, K.P., Chen, E.S., Zhang, L.
Published 2021

Cellular factories for coenzyme Q10 production

by Lee, S.Q.E, Tan, T.S, Kawamukai, M, Chen, E.S
Published 2020

Gold nanoparticles induce serum amyloid A 1–Toll-like receptor 2 mediated NF-kB signaling in lung cells in vitro

by Ng, CT, Yip, GWC, Chen, ES, Poh, WYR, Bay, BH, Yung, LYL
Published 2023

Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast

by Lim, K.K., Nguyen, T.T.T., Li, A.Y., Yeo, Y.P., Chen, E.S.
Published 2022

NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity

by Li, C, Zhang, Y, Yang, Q, Ye, F, Sun, S.Y, Chen, E.S, Liou, Y.-C
Published 2020

XRibonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function

by Mukarami H., Goto D.B., Toda T., Chen E.S., Grewal S.I., Martienssen R.A., Yanagida M.
Published 2018

Cellular Robustness Conferred by Genetic Crosstalk Underlies Resistance against Chemotherapeutic Drug Doxorubicin in Fission Yeast

by Tay, Z., Eng, R.J., Sajiki, K., Lim, K.K., Tang, M.Y., Yanagida, M., Chen, E.S.
Published 2014

Regulation of transcriptional silencing and chromodomain protein localization at centromeric Heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast

by Ren, B., Tan, H.L., Nguyen, T.T.T., Sayed, A.M.M., Li, Y., Mok, Y.-K., Yang, H., Chen, E.S.
Published 2021

Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast

by Lim, K.K, Ong, T.Y, Tan, Y.R, Yang, E.G, Ren, B, Seah, K.S, Yang, Z, Tan, T.S, Dymock, B.W, Chen, E.S
Published 2020

P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells

by Tay, Z., Koo, S.H., Nguyen, T.T.T., Tan, T.S., Chen, M.L., Chin, C.F., Lim, K.K., Ang, W.H., Bay, B.H., Lee, E.J.D., Chen, E.S.
Published 2014

Prolyl isomerization of the CENP-A N-Terminus regulates centromeric integrity in fission yeast

by Tan, H.L., Lim, K.K., Yang, Q., Fan, J.-S., Sayed, A.M.M., Low, L.S., Ren, B., Lim, T.K., Lin, Q., Mok, Y.-K., Liou, Y.-C., Chen, E.S.
Published 2021

Crystal structure and functional analysis of human C1ORF123

by Rahaman, S.N.A, Yusop, J.M, Mohamed-Hussein, Z.-A, Aizat, W.M, Ho, K.L, Teh, A.-H, Waterman, J, Tan, B.K, Tan, H.L, Li, A.Y, Chen, E.S, Ng, C.L
Published 2020