Celastrol alleviates gamma irradiation-induced damage by modulating diverse inflammatory mediators

by Wang, H., Ahn, K.S., Alharbi, S.A., Shair, O.H.M., Arfuso, F., Chinnathambi, A., Tang, F.R.
Published 2021

Attenuation of STAT3 signaling cascade by daidzin can enhance the apoptotic potential of bortezomib against multiple myeloma

by Yang, M.H., Jung, S.H., Chinnathambi, A., Alahmadi, T.A., Alharbi, S.A., Sethi, G., Ahn, K.S.
Published 2021

Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators

by Wang H., Sim M.-K., Loke W.K., Chinnathambi A., Alharbi S.A., Tang F.R., Sethi G.
Published 2020

Formononetin regulates multiple oncogenic signaling cascades and enhances sensitivity to bortezomib in a multiple myeloma mouse model

by Kim, C., Lee, J.H., Ko, J.-H., Chinnathambi, A., Alharbi, S.A., Shair, O.H.M., Sethi, G., Ahn, K.S.
Published 2021

Gamma Radiation-Induced Disruption of Cellular Junctions in HUVECs Is Mediated through Affecting MAPK/NF- κB Inflammatory Pathways

by Wang, H., Segaran, R.C., Chan, L.Y., Aladresi, A.A.M., Chinnathambi, A., Alharbi, S.A., Sethi, G., Tang, F.R.
Published 2021

Fangchinoline, a bisbenzylisoquinoline alkaloid can modulate cytokine-impelled apoptosis via the dual regulation of NF-?B and AP-1 pathways

by Jung, Y.Y., Shanmugam, M.K., Chinnathambi, A., Alharbi, S.A., Shair, O.H.M., Um, J.-Y., Sethi, G., Ahn, K.S.
Published 2021

The IκB kinase inhibitor ACHP targets the STAT3 signaling pathway in human non-small cell lung carcinoma cells

by Lee, J.H., Mohan, C.D., Basappa, S., Rangappa, S., Chinnathambi, A., Alahmadi, T.A., Alharbi, S.A., Kumar, A.P., Sethi, G., Ahn, K.S., Rangappa, K.S.
Published 2021

2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway

by Ko, J.-H, Lee, J.H, Jung, S.H, Lee, S.-G, Chinnathambi, A, Alharbi, S.A, Yang, W.M, Um, J.-Y, Sethi, G, Ahn, K.S
Published 2020

The multifaceted role of curcumin in cancer prevention and treatment

by Shanmugam M.K, Rane G, Kanchi M.M, Arfuso F, Chinnathambi A, Zayed M.E, Alharbi S.A, Tan B.K.H, ALAN PREM KUMAR, Sethi G
Published 2016

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

by Somu, C., Mohan, C.D., Ambekar, S., Dukanya, Rangappa, S., Baburajeev, C.P., Sukhorukov, A., Mishra, S., Shanmugam, M.K., Chinnathambi, A., Awad Alahmadi, T., Alharbi, S.A., Basappa, Rangappa, K.S.
Published 2021

Viperatoxin-II: A novel viper venom protein as an effective bactericidal agent

by Samy, R.P, Stiles, B.G, Chinnathambi, A, Zayed, M.E, Alharbi, S.A, Franco, O.L, Rowan, E.G, Kumar, A.P, Lim, L.H.K, Sethi, G
Published 2020

Isorhynchophylline, a potent plant alkaloid, induces apoptotic and anti-metastatic effects in human hepatocellular carcinoma cells through the modulation of diverse cell signaling...

by Lee, H, Baek, S.H, Lee, J.H, Kim, C, Ko, J.-H, Lee, S.-G, Chinnathambi, A, Alharbi, S.A, Yang, W.M, Um, J.-Y, Sethi, G, Ahn, K.S
Published 2020

Novel 1,3,4-oxadiazole targets STAT3 signaling to induce antitumor effect in lung cancer

by Malojirao, V.H., Girimanchanaika, S.S., Shanmugam, Muthu K., Sherapura, A., Dukanya, Metri, P.K., Vigneshwaran, V., Chinnathambi, A., Alharbi, S.A., Rangappa, S., Mohan, C.D., Basappa, Prabhakar, B.T., Rangappa, K.S.
Published 2021

Trisubstituted-imidazoles induce apoptosis in human breast cancer cells by targeting the oncogenic PI3K/Akt/mTOR signaling pathway

by Mohan C.D., Srinivasa V., Rangappa S., Mervin L., Mohan S., Paricharak S., Baday S., Li F., Shanmugam M.K., Chinnathambi A., Zayed M.E., Alharbi S.A., Bender A., Sethi G., Basappa, Rangappa K.S.
Published 2018

NGAL is downregulated in oral squamous cell carcinoma and leads to increased survival, proliferation, migration and chemoresistance

by Monisha J., Roy N.K., Padmavathi G., Banik K., Bordoloi D., Khwairakpam A.D., Arfuso F., Chinnathambi A., Alahmadi T.A., Alharbi S.A., Sethi G., Kumar A.P., Kunnumakkara A.B.
Published 2019

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

by Nirvanappa A.C., Mohan C.D., Rangappa S., Ananda H., Sukhorukov A.Y., Shanmugam M.K., Sundaram M.S., Nayaka S.C., Girish K.S., Chinnathambi A., Zayed M.E., Alharbi S.A., Sethi G., Basappa, Rangappa K.S.
Published 2018

Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma

by Lee, J.H., Mohan, C.D., Deivasigamani, A., Jung, Y.Y., Rangappa, S., Basappa, S., Chinnathambi, A., Alahmadi, T.A., Alharbi, S.A., Garg, M., Lin, Z.-X., Rangappa, K.S., Sethi, G., Hui, K.M., Ahn, K.S.
Published 2021

Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase

by Baek, S.H, Lee, J.H, Kim, C, Ko, J.-H, Ryu, S.-H, Lee, S.-G, Yang, W.M, Um, J.-Y, Chinnathambi, A, Alharbi, S.A, Sethi, G, Ahn, K.S, Choi, D.-K., Ganesan, P.
Published 2020

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

by Dai X., Wang L., Deivasigamni A., Looi C.Y., Karthikeyan C., Trivedi P., Chinnathambi A., Alharbi S.A., Arfuso F., Dharmarajan A., Goh B.C., Hui K.M., Kumar A.P., Mustafa M.R., Sethi G.
Published 2020

Inhibition of p300 Lysine Acetyltransferase activity by Luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model

by Selvi, R.B, Swaminathan, A, Chatterjee, S, Shanmugam, M.K, Li, F, Ramakrishnan, G.B, Siveen, K.S, Chinnathambi, A, Emam Zayed, M, Alharbi, S.A, Basha, J, Bhat, A, Vasudevan, M, Dharmarajan, A, Sethi, G, Kundu, T.K
Published 2020